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目的:研究不同剂量甘露醇治疗脑出血的临床效果并进行分析。方法:选择于2011年2月至2014年2月至我院神经内科就诊且具有完整临床资料的脑出血患者230例,随机分为观察组与对照组各115人,对照组给予常规治疗、20%甘露醇250ml脱水治疗,观察组给予常规治疗、20%甘露醇125ml脱水治疗。所有经受治疗的患者甘露醇的使用频率相同,使用时间均为30天,分别于用药前,用药15d,用药30d记录并比较两组患者的血肿情况及中国卒中评分(CSS)。结果:经过15d治疗,观察组血肿体积明显低于对照组,p<0.05,差异有统计学意义;30d时,观察组CSS评分明显低于对照组CSS评分,p<0.05,差异有统计学意义。结论:小剂量甘露醇治疗脑出血的临床效果更好,更值得临床推广。
Objective: To study the clinical effect of different doses of mannitol in the treatment of cerebral hemorrhage and analyze. Methods: A total of 230 patients with intracerebral hemorrhage who were admitted to our department of neurology from February 2011 to February 2014 with complete clinical data were randomly divided into observation group (115 cases) and control group (115 cases). The control group received routine treatment and 20 % Mannitol 250ml dehydration treatment, the observation group given conventional treatment, 20% mannitol 125ml dehydration treatment. All patients treated with the same frequency of use of mannitol, the use of time were 30 days, respectively, before treatment, medication 15d, medication 30d recorded and compared the two groups of patients with hematoma and stroke score (CSS). Results: After 15 days of treatment, the volume of hematoma in the observation group was significantly lower than that of the control group, p <0.05, the difference was statistically significant. On the 30th day, the CSS score of the observation group was significantly lower than that of the control group, p <0.05, the difference was statistically significant . Conclusion: A small dose of mannitol in the treatment of cerebral hemorrhage clinical effect is better, more worthy of clinical promotion.