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目的:观察还原型谷胱甘肽(GSH)注射液治疗慢性乙型肝炎的疗效和安全性。方法:采用GSH注射液治疗慢性乙型肝炎38例,并选择38例采用维生素C、门冬酸钾镁、益肝灵治疗的慢性乙型肝炎患者作为对照组,对肝功能、肾功能、血常规进行观察。结果:治疗组血清总胆红素(TBIL)、丙氨酸转氨酶(ALT)下降较对照组显著(P<0.01)。治疗组血清总蛋白上升较对照组显著(P<0.05)。治疗组外周血白细胞(WBC)、血小板(PLT)上升较对照组显著(P<0.01)。在治疗过程中,未发生与本药有关的严重不良反应。结论:GSH注射液治疗慢性乙型肝炎疗效显著。
Objective: To observe the efficacy and safety of reduced glutathione (GSH) injection in the treatment of chronic hepatitis B patients. Methods: 38 cases of chronic hepatitis B were treated with GSH injection and 38 cases of chronic hepatitis B patients treated with vitamin C, potassium aspartate and magnesium magnesium aspartate were selected as the control group, and liver function, renal function, blood Routine observation. Results: Serum total bilirubin (TBIL) and alanine aminotransferase (ALT) in the treatment group decreased significantly compared with the control group (P <0.01). The total serum protein in the treatment group increased significantly compared with the control group (P <0.05). The WBC and PLT in treatment group were significantly higher than those in control group (P <0.01). In the course of treatment, no serious adverse reactions occurred with the drug. Conclusion: The effect of GSH injection on chronic hepatitis B is significant.