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作者从荷兰Nijmegen大学附属医院糖尿病门诊1988年4月~1990年4月定期随诊的530名IDDM病人中选择了情况大致相同的30例自愿参加为期2年研究的病人。其中1例用氨酸心安2周出现严重头痛停药,其余29例全部完成2年研究计划。29例随机分为两组,开搏通组15例(男12例,女3例),平均年龄37±2岁,糖尿病病程26±2年。氨酰心安组14例(男11例,女3例),平均年龄39±3岁,糖尿病病程26±2年。全部病人均有视网膜病变。11例有高血压(BP>140/90mmHg),其中5
The authors selected 30 patients who volunteered for a 2-year study from 530 IDDM patients who were regularly followed up from April 1988 to April 1990 in the Diabetes Clinic of the Affiliated Hospital of Nijmegen University in the Netherlands. Among them, 1 patient had serious headache withdrawal with 2-hour administration of angiotensin, and the remaining 29 patients completed the 2-year research plan. Twenty-nine patients were randomly divided into two groups. Fifteen patients (12 males and 3 females) were treated with Caifei. The mean age was 37 ± 2 years and duration of diabetes was 26 ± 2 years. Atenolol in 14 cases (11 males and 3 females), with an average age of 39 ± 3 years, duration of diabetes 26 ± 2 years. All patients have retinopathy. Eleven patients had hypertension (BP> 140/90 mmHg) of which 5