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目的:观察四黄调胃汤联合PPI三联疗法治疗幽门螺杆菌(Hp)相关性胃炎及消化性溃疡的临床疗效。方法:分别采用三种不同方法治疗幽门螺杆菌相关性胃炎及消化性溃疡,缓解患者脾气虚、湿热气滞症状,观察中医治疗消化性溃疡、慢性胃炎的临床效果及对幽门螺杆菌的根除作用。结果:四黄调胃汤联合PPI三联疗法对相关性胃炎及消化性溃疡可起到一定的改善作用,有利于加强愈合,幽门螺杆菌根除率较四黄调胃汤、PPI三联疗法明显提高。三种方法治疗胃炎均有明显的疗效,四黄调胃汤联合PPI三联疗法、单纯四黄调胃汤疗效及消化性溃疡改善情况优于PPI三联疗法。结论:四黄调胃汤联合PPI三联疗法治疗幽门螺杆菌相关性胃炎及消化性溃疡综合疗效优于单纯中药、西药治疗。
Objective: To observe the clinical efficacy of “Sihuang Tiawei Decoction” combined with PPI triple therapy in the treatment of Helicobacter pylori (Hp) -related gastritis and peptic ulcer. Methods: Three different methods were used to treat Helicobacter pylori-associated gastritis and peptic ulcer respectively to relieve symptoms of spleen deficiency, damp-heat and qi stagnation. To observe the clinical effect of Chinese medicine treatment of peptic ulcer and chronic gastritis and eradication of Helicobacter pylori . Results: Sihuangtangwei Decoction combined with PPI triple therapy could improve the related gastritis and peptic ulcer, improve healing, and cure H. pylori more than that of Sihuangfeizhiweitang and PPI triple therapy. Three methods of treatment of gastritis have a significant effect, Si Huang Wei Stomach combined with PPI triple therapy, simple Si Huang Tientsi Tang efficacy and improvement of peptic ulcer PPI triple therapy. Conclusion: The combination of Sihuangtangwei Decoction and PPI triple therapy in treating Helicobacter pylori-associated gastritis and peptic ulcer is better than simple Chinese medicine and Western medicine.