氨茶碱治疗哮喘已达50年,迄今仍为国内外防治各种哮喘的常用药物之一。本文就氨茶碱合理应用的有关问题予以简述。药动学基础茶碱在胃肠道吸收良好,其生物利用度为96～98%。食物干扰茶碱缓释片的吸收速率,便(?)浓度的时间延迟,但总的生物利用(?)食物或进液量的影响。 Aminophylline treatment of asthma has reached 50 years, so far is still one of the commonly used drugs for prevention and treatment of various asthma at home and abroad. This article briefly discusses the issues related to the rational application of aminophylline. Basic pharmacokinetics of theophylline absorption in the gastrointestinal tract, the bioavailability of 96 to 98%. The rate of absorption of theophylline sustained-release tablets by food disrupts the time delay of the (?) Concentration, but the total bioavailability (?) Of the food or the amount of fluid infused.