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目的分析研究中西医联合治疗早期糖尿病肾病的临床疗效,旨在为进一步规范我国早期糖尿病肾病的治疗提供一定的依据。方法选取2009年3月到2013年3月在本院接收治疗的早期糖尿病肾病患者100例,并随机分为观察组与对照组,各组患者50例,对照组50例患者接受西医常规治疗,观察组50例患者在接受与对照组相同的西医常规治疗基础上联合中药治疗。治疗三个月之后,对比分析观察组与对照组的临床治疗效果与不良反应发生率。结果在对照组50例患者中,其治疗显效的患者有14例,治疗有效的患者有23例,治疗无效的患者有13例,治疗总有效率达到74%。在观察组50例患者中,治疗出现显效的患者有28例,治疗有效的患者为19例,治疗无效的患者有3例。治疗总有效率为94%。分析两组数据能够发现,观察组患者治疗结束之后总有效率要比对照组患者总有效率高,差异有显著统计学意义(P<0.05),所有患者在治疗过程中均没有出现心悸、胸痛、皮疹以及血管性水肿、心动过速等不良反应。结论中西医联合治疗早期糖尿病肾病有着治疗效果确定、不良反应发生率低等诸多优点,值得在临床上推广使用。
Objective To analyze the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of early diabetic nephropathy and to provide some evidences for further regulating the treatment of early diabetic nephropathy in our country. Methods From March 2009 to March 2013, 100 patients with early diabetic nephropathy who received treatment in our hospital were selected and randomly divided into observation group and control group. 50 patients in each group and 50 patients in control group received routine western medicine treatment. Fifty patients in the observation group were treated with traditional Chinese medicine on the basis of the same Western medical treatment as the control group. Three months after treatment, comparative analysis of the observation group and the control group clinical treatment and adverse reactions. Results Among the 50 patients in the control group, 14 were effective in treatment, 23 in effective treatment, 13 in ineffective treatment and 74% in total. Of the 50 patients in the observation group, 28 were clinically effective, 19 were effective, and 3 were ineffective. The total effective rate was 94%. Analysis of the two groups of data can be found, the total effective rate of observation group patients after treatment than the control group, the total effective rate was significantly higher, the difference was statistically significant (P <0.05), all patients did not appear during the treatment of palpitations, chest pain , Rash and angioedema, tachycardia and other adverse reactions. Conclusion The combination of traditional Chinese and western medicine treatment of early diabetic nephropathy with the treatment effect is determined, the incidence of adverse reactions and many other advantages, it is worth promoting in clinical use.