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Objective:Important studies of cardiopulmonary resuscitation (CPR) techniques influence the development of new guidelines.We systematically reviewed the efficacy of some important studies of CPR.Data Sources:The data analyzed in this review are mainly from articles included in PubMed and EMBAS E,published from 1964 to 2014.Study Selection:Original articles and critical reviews about CPR techniques were selected for review.Results:The survival rate after out-of-hospital cardiac arrest (OHCA) is improving.This improvement is associated with the performance of uninterrupted chest compressions and simple airway management procedures during bystander CPR.Real-time feedback devices can be used to improve the quality of CPR.The recommended dose,timing,and indications for adrenaline (epinephrine) use may change.The appropriate target temperature for targeted temperature management is still unclear.Conclusions:New studies over the past 5 years have evaluated various aspects of CPR in OHCA.Some of these studies were high-quality randomized controlled trials,which may help to improve the scientific understanding of resuscitation techniques and result in changes to CPR guidelines.