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目的评价保妇康栓和朗依(硝呋太尔制霉素阴道软胶囊)治疗妊娠合并外阴阴道假丝酵母菌病的经济性,为合理用药及相关决策提供参考。方法本研究基于二次文献进行Meta分析,以获取药物经济学评价中的有效性、安全性数据;结合相应治疗规范与临床专家建议,确定治疗路径并据此计算总的直接医疗成本。基于全社会角度,运用最小成本分析法,进行药物经济学评价。结果保妇康栓组的总直接医疗成本低于朗依组。敏感性分析证明确定性分析结果稳定。结论与朗依相比,保妇康栓治疗妊娠合并外阴阴道假丝酵母菌病的经济性更好。
Objective To evaluate the economical efficiency of Baofukang Suppository and Longyin (nifuratel nystocin vaginal soft capsule) in the treatment of vulvovaginal candidiasis in pregnancy and to provide reference for rational drug use and related decision-making. Methods Based on the secondary literature, Meta-analysis was conducted to obtain the validity and safety data of the pharmacoeconomic evaluation. Based on the corresponding treatment criteria and clinical experts’ suggestions, the treatment path was determined and the total direct medical costs were calculated accordingly. Based on the perspective of the whole society, using the method of least cost analysis, the evaluation of pharmacoeconomics. Results Baofukang suppository total direct medical costs less than Ron group. Sensitivity analysis shows that the deterministic analysis is stable. Conclusion Compared with Longyi, Baofukang suppository is more economical to treat pregnancy with vulvovaginal candidiasis.