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人胚胎干细胞(human embryonic stem cells,hESCs)是源自人早期胚胎内细胞团(inner cell mass)或原始生殖细胞(primordial germ cells)的多潜能细胞类群,能长期增殖并保持未分化状态和核型完整,具有分化为机体所有类型细胞的潜能,最有希望成为细胞器官移植、基因治疗的种子源细胞。自1998年首次成功建立hESCs系以来[1-2],针对hESCs建系及其临床应用的伦理学、安全性和有效性等问题,科学家们进行了广泛而卓有成效的研究。本文主要对hESCs临床应用所面
Human embryonic stem cells (hESCs) are pluripotent cell populations derived from the inner cell mass or primordial germ cells of human early embryos, capable of long-term proliferation and maintaining an undifferentiated state and nucleus Complete, with the potential to differentiate into all types of cells in the body, the most promising as a seed cell transplantation, gene therapy of seed cells. Since the first successful establishment of hESCs in 1998 [1-2], scientists have conducted extensive and fruitful research on the ethical, safety and efficacy issues of hESCs and their clinical applications. This article focuses on the clinical application of hESCs