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1964年6月至10月,我科共收治中毒型痢疾患儿25名,其中轻型15例,重型8例,极重型2例。采用以人工冬眠为主的综合治疗者12例,以阿托品(Atropinum)为主进行治疗者13例,全部治愈。现将临床观察及治疗经过初步小结如下。实施方法及疗效(一)人工冬眠组:1.方法:采用冬眠Ⅱ号[每毫升含冬眠灵(Chlorpromazini Hydrochloridum)及非那更(Promethazini Hydrochloridum)各10毫克],其剂量为2～3毫克/公斤,肌注,每2～3小时一次,较以往用量偏大(1～2毫克/公斤)。适当配合鲁米那尔(Lum-mal)(5～10毫克/公斤)肌注,及水合氯醛(ChloraliHydras)(50～80毫克/公斤)鼻饲,待患者安静入睡,对弱刺激无反应时,在大血管(浅表部位者如颈动脉、股动脉)加冰囊降温。
From June to October 1964, our department treated 25 children with poisoned diarrhea, of which 15 were light, 8 were heavy and 2 were extremely heavy. Using synthetic hibernation-based comprehensive treatment in 12 cases, mainly in the treatment of Atropinum (13 cases, all cured. Now clinical observation and treatment after a preliminary summary is as follows. Methods and Efficacy (I) Artificial hibernation group: 1. Methods: Hypnotic II (10 mg each containing Chlorpromazini Hydrochloridum and Promethazini Hydrochloridum) was administered in a dose of 2 to 3 mg / Kg, intramuscular injection, once every 2 to 3 hours, larger than the previous dose (1 ~ 2 mg / kg). With appropriate intramuscular injection of Lum-mal (5-10 mg / kg) and Chlorali Hydras (50-80 mg / kg) nasal feeding, the patient is asleep and does not respond to weak stimulation , In the large vessels (superficial parts such as carotid artery, femoral artery) plus ice capsule cooling.