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目的探讨ＡＢＯ血型、个性、ＨＬＡＤＱ与矽肺易感性的关系。方法以某钢铁公司１９９７年１２月确诊的Ⅰ期矽肺男性患者为对象。与病例同性别、同工种、在同一车间工作、开始接尘时间及累积接尘工龄相差不超过２年、年龄相差不超过５岁、于１９９７年１２月拍片证实非矽肺接尘工人为对照。病例与对照按１∶１配比。进行了ＡＢＯ血型分布、艾森克个性问卷调查和ＨＬＡＤＱ水平测定。结果矽肺组与对照组比较，血型分布无明显差异；矽肺组外倾性格的人所占比例高于对照组，ＨＬＡＤＱ水平低于对照组。结论ＡＢＯ血型与矽肺易感性无明显关联；外倾性格的人、ＨＬＡＤＱ水平较低者可能对矽肺易感。
Objective To investigate the relationship between ABO blood type, personality, HLADQ and silicosis susceptibility. Methods A stage I silicosis male patient diagnosed in December 1997 by a steel company was selected as the object. With the same sex with the case, with the same job, work in the same workshop, began to catch the dust time and cumulative dust Duty difference no more than 2 years, the difference between the age of not more than 5 years old, in December 1997 filming confirmed non-silicosis dust workers as a control. Case and control by 1: 1 ratio. ABO blood group distribution, Eysenck personality questionnaire and HLA DQ level determination. Results Compared with the control group, there was no significant difference in the distribution of blood group in the silicosis group. The proportion of extranodal personality in the silicosis group was higher than that in the control group, and the level of HLADQ was lower than that in the control group. Conclusion ABO blood group is not significantly associated with susceptibility to silicosis; extraverted personality, HLA-DQ lower levels may be susceptible to silicosis.