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目的探讨妊娠合并卵巢肿瘤的临床特征、处理及对妊娠结局的影响,为提高妊娠合并卵巢肿瘤的诊治水平提供资料。方法对解放军第二○二医院2003年1月～2009年12月收治的248例经手术和病理诊断确诊的妊娠合并卵巢肿瘤患者的临床资料进行回顾性分析。结果本组病例妊娠合并卵巢肿瘤发生率为0.49%,其中妊娠合并卵巢良性肿瘤131例(52.82%),以成熟性畸胎瘤最多见(22.18%);瘤样病变113例,占45.57%,以子宫内膜样囊肿及黄体囊肿多见;恶性肿瘤4例,占1.61%。212例患者行肿瘤切除术或附件切除术,4例妊娠合并卵巢恶性肿瘤患者中3例接受了术后化疗。常规产前检查及超声诊断病例192例,占孕期发现总例数的77.42%;有14例出现并发症行急诊手术,扭转9例,破裂5例;67例选择孕14～18周手术治疗,57例妊娠至足月。结论盆腔检查及超声检查在对妊娠期卵巢肿瘤的诊断和监测上具有重要意义,妊娠合并卵巢肿瘤治疗以肿瘤切除术为主,孕中期的手术干预是安全的。
Objective To investigate the clinical features, treatment and pregnancy outcome of pregnancy complicated with ovarian tumors and provide information for improving the diagnosis and treatment of ovarian tumors in pregnancy. Methods A retrospective analysis was performed on the clinical data of 248 patients with pregnancy complicated with ovarian tumor diagnosed by operation and pathology from January 2003 to December 2009 in the 202 Hospital of PLA. Results The incidence of pregnancy complicated with ovarian cancer in this group was 0.49%, of which 131 cases (52.82%) were benign ovarian tumors in pregnancy, the most common was mature teratoma (22.18%); the 113 cases (45.57% Endometrioid cyst and luteal cyst more common; 4 cases of malignant tumors, accounting for 1.61%. 212 patients underwent tumor resection or adjuvant resection and 3 of 4 patients with pregnancy complicated with ovarian cancer received postoperative chemotherapy. 192 cases of routine prenatal examination and ultrasound diagnosis, accounting for 77.42% of the total number of cases found during pregnancy; 14 cases of complications of emergency surgery, 9 cases of reverse, rupture in 5 cases; 67 cases of pregnant 14 to 18 weeks of surgical treatment, 57 cases of pregnancy to term. Conclusions Pelvic examination and ultrasonography are important in the diagnosis and monitoring of ovarian tumors in pregnancy. Tumor resection is the main treatment for pregnancy complicated with ovarian tumors, and surgical intervention in the second trimester is safe.