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目的:探讨联合检测血清人绒毛膜促性腺激素(HCG)和孕酮(P)在异位妊娠早期诊断中的意义。方法:应用化学发光法分别检测60例正常妊娠和41例异位妊娠的妇女在4～6周孕龄时的HCG和孕酮的水平。结果:异位妊娠组第4孕周时孕酮水平明显低于正常妊娠组(P<0.05),HCG水平与正常妊娠组比较差异无统计学意义(P>0.05);异位妊娠组第5、6孕周时HCG和孕酮水平均显著低于正常妊娠组(P<0.001)。结论:HCG和孕酮联合动态定量测定有助于异位妊娠的早期诊断,对提高诊治水平具有重要的临床意义。
Objective: To explore the significance of combined detection of serum human chorionic gonadotropin (HCG) and progesterone (P) in the early diagnosis of ectopic pregnancy. Methods: The levels of HCG and progesterone in pregnant women of 60 normal pregnant women and 41 ectopic pregnant women at gestational ages of 4 to 6 weeks were detected by chemiluminescence method. Results: The level of progesterone in the fourth gestational week in ectopic pregnancy group was significantly lower than that in the normal pregnancy group (P <0.05), and there was no significant difference in HCG level between the ectopic pregnancy group and the normal pregnancy group (P> 0.05) , The level of HCG and progesterone at 6 weeks gestation was significantly lower than that of the normal pregnancy group (P <0.001). Conclusions: Combined dynamic quantitative determination of HCG and progesterone is helpful for the early diagnosis of ectopic pregnancy and has important clinical significance for improving the diagnosis and treatment.