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目的对阿司匹林联合氯吡格雷治疗进展型缺血性卒中的有效性和安全性进行探讨。方法选择本院收治的69例进展型缺血性卒中患者,分成阿司匹林组(对照组)、阿司匹林联合氯吡格雷组(治疗组),持续治疗21 d,患者治疗前后分别进行NIHSS评分体系对比分析。结果治疗组患者总有效率高于对照组患者(P<0.05)。结论阿司匹林联合氯吡格雷治疗进展型缺血性卒中的疗效显著,能够阻止病情恶化,促进神经功能的恢复,降低致残率,治疗期间未发生严重出血事件,安全性较高。
Objective To investigate the efficacy and safety of aspirin combined with clopidogrel in the treatment of advanced ischemic stroke. Methods Sixty-nine patients with progressive ischemic stroke admitted to our hospital were divided into aspirin group (control group), aspirin group and clopidogrel group (treatment group) for 21 days. The NIHSS score system was compared before and after treatment . Results The total effective rate in the treatment group was higher than that in the control group (P <0.05). Conclusion Aspirin combined with clopidogrel is effective in treating progressive ischemic stroke, which can prevent the progression of the disease, promote the recovery of neurological function, reduce the morbidity and disability, and have no serious bleeding during the treatment. It is safe and safe.