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Objective:To explore the role of metallothionein-3 gene in lung adenocarcinoma. Methods: cDNA microarray and northern blots analysis were used to study the expression of metallothionein-3 in lung adenocarcinoma. Results: The results of cDNA microarray showed that metallothionein-3 gene was expressed highly to normal lung tissues at the average ratio of 7. 8 (Cy5/Cy3) in lung adenocarcinoma tissues. Northern blots confirmed the ratio changes detected from the microarray. Conclusion: Metallothionein-3 may play an important role in the lung adenocarcinoma development.
Objective: To explore the role of metallothionein-3 gene in lung adenocarcinoma. Methods: cDNA microarray and northern blots analysis were used to study the expression of metallothionein-3 in lung adenocarcinoma. Results: The results of The cDNA microarray of that metallothionein-3 gene was expressed highly to normal lung tissues at the average ratio of 7. 8 (Cy5 / Cy3) in lung adenocarcinoma tissues. Northern blots confirmed the ratio changes detected from the microarray. Conclusion: Metallothionein-3 may play an important role in the lung adenocarcinoma development.