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目的探讨联合复方醋酸棉酚片配伍米非司酮治疗子宫肌瘤方案的临床效果进行调查研究。方法选取2012年1月至6月期间子宫肌瘤患者80例,随机分为对照组和观察组,各40例,对照组患者仅服用米非司酮,观察组在对照组的基础上加服复方醋酸棉酚片,对比观察组和对照组患者的治疗效果及不良反应的差异。结果观察组和对照组的患者肌瘤体积治疗后均明显减小,加服复方醋酸棉酚片的观察组减小幅度大于对照组,差异有统计学意义;观察组较对照组平均血红蛋白提高,对照组治疗总有效率明显低于观察组,差异有统计学意义。结论两种方案对于子宫肌瘤的治疗均有效果,复方醋酸棉酚片配伍米非司酮治疗子宫肌瘤的疗效更明显,且不良反应小。
Objective To investigate the clinical efficacy of combined compound gossypol acetate tablets and mifepristone in the treatment of uterine fibroids. Methods 80 patients with uterine fibroids between January 2012 and June 2012 were randomly divided into control group and observation group, 40 cases in each group. Patients in control group were treated with mifepristone only. The observation group was served on the basis of control group Compound gossypol acetate tablets, the control group and the control group of patients with treatment and adverse reaction differences. Results The volume of fibroids in observation group and control group were significantly decreased after treatment. The decrease in the observation group treated with compound gossypol acetate was larger than that in the control group, the difference was statistically significant. The average hemoglobin in the observation group was higher than that in the control group, The total effective rate of the control group was significantly lower than the observation group, the difference was statistically significant. Conclusion Both of the two regimens have the same effect on the treatment of uterine fibroids. The curative effect of compound acetaminophen tablets combined with mifepristone on uterine fibroids is more obvious and the adverse reaction is small.