The aim of the work was confined to the investigation of the epileptic activity dynamics under conditions of extremely high frequency electromagnetic waves(EHF) radiation(7.1 mm,0.1 mW/cm2) upon focal epileptic activity,which was penicillin-induced(10 000 IU/ml) in frontal zone of the brain cortex in myorelaxed and artificially ventilated rats under acute experimental condition.It was established that preliminarily performed hypogeomagnetic period(3.0 h) with the inductivity of geomagnetic field reduction not less than by 100 times caused the intensification of antiepileptic effects of EHF(15.0 min of exposition).It was pronounced in the form of decrease of foci intensity and significant reduction of life-span of foci-up to 115.3±13.4 minutes,which was both significant when compared with separate effects of hypogeomagnetic influence(187.3±12.5 min) and EHF(15.0 minutes of exposition) effect(164.2±12.5 minutes)(P <0.05). The aim of the work was confined to the investigation of the epileptic activity dynamics under conditions of extremely high frequency electromagnetic waves (EHF) radiation (7.1 mm, 0.1 mW / cm2) upon focal epileptic activity, which was penicillin-induced (10,000 IU / ml) in frontal zone of the brain cortex in myorelaxed and artificially ventilated rats under acute experimental condition. It was established that preliminarily performed hypogeomagnetic period (3.0 h) with the inductivity of geomagnetic field reduction not less than by 100 times caused the intensification of antiepileptic effects of EHF (15.0 min of exposition). It was pronounced in the form of decrease of foci intensity and significant reduction of life-span of foci-up to 115.3 ± 13.4 minutes, which was both significant when compared with separate effects of hypogeomagnetic influence (187.3 ± 12.5 min) and EHF (15.0 minutes of exposition) effect (164.2 ± 12.5 minutes) (P <0.05).