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应用IHA法对1318名15～45岁育龄妇女进行了破伤风抗毒素水平测定，阳性率8.80％，保护率7.97％，GMT0．0026IU／ml。抗体阳性率随年龄增大呈下降趋势；城镇与农村育龄妇女的抗体阳性率和保护率均无明显差异。对其中379名18～35岁育龄妇女进行破类免疫，接种1，2，3针后的抗体阳性率，由免前的7.12％分别上升到88．34％、95．33％和100％，保护率由免前的6.33％分别上升到86．02％、93．93／和100％；GMT由免前的0.002IU／ml分别上升到0.26IU／ml、0．38U／ml和0．68IU／ml。各针次间的抗体阳性率、保护率和GMT均有显著差异。而各年龄组间的血清学效果则无明显差异。
The IHA method was used to determine the level of antitoxin in 1318 women of childbearing age from 15 to 45, the positive rate was 8.80%, the protection rate was 7.97% and the GMT was 0.0026IU / ml. The positive rate of antibody showed a decreasing trend with age. There was no significant difference in antibody positive rate and protection rate among women of childbearing age in urban and rural areas. Among 379 women of childbearing age from 18 to 35, the antibody positive rates after vaccination were increased from 7.12% to 88.34%, 95.33% and 100% respectively, The protection rate increased from 6.33% to 86.02%, 93.93% and 100% respectively. GMT increased from 0.002IU / ml to 0.26IU / ml, 0.38U / ml and 0.68IU / Ml. The antibody positive rate, protection rate and GMT between each needle were significantly different. There was no significant difference in the serological results among all age groups.