1临床资料患儿,男,9岁9月。因“行动笨拙、学习困难9年”就诊。患儿自1岁左右出现发育行为较同龄儿落后,1岁7月走稳,动作不灵活,常摔跤。语言少,可以与人交流,但反应迟钝。上学后成绩差,握笔姿势笨拙,写字慢,字体别扭,学习困难。平时饮食一般,睡眠可。患儿系农村家庭,家中土法接生,自然足月分娩,出生时无窒息史。父母非近亲婚配,有一姐一妹,均无异常。查体:体重22.0kg(-s),身高 1 clinical data in children, male, 9 years old in September. Because of “clumsy operation, learning difficulties for 9 years ” treatment. Children from the age of 1 appear to develop behavior than the same age children behind, 1-year-old stable in July, action is not flexible, often wrestling. Lack of language, can communicate with others, but unresponsive. Poor grades after school, clumsy pen posture, slow writing, awkward fonts, learning difficulties. Normal diet, sleep can be. Pediatric Department of rural families, home Tufa, natural full-term childbirth, birth without asphyxia history. Parents non-relatives marriage, a sister, a sister, are normal. Physical examination: weight 22.0kg (-s), height