溶解度溶解度在药物代谢动力学、化学稳定性直至药物处方设计方面通常是一个重要的因素。如前所述它肯定是控制溶出速率的主要因素。化合物的溶解度基本上取决于溶质的物理化学性质。例如,在同一系列中,熔点较低的化合物,品格能较低,后者则提示溶解度 Solubility Solubility is often an important factor in pharmacokinetics, chemical stability, and drug prescription design. It is certainly a major factor in controlling the rate of dissolution as previously described. The solubility of a compound depends essentially on the physicochemical properties of the solute. For example, in the same series, compounds with lower melting points have a lower quality, whereas the latter indicate a solubility