庆大霉素属广谱抗生素,杀菌力较强,且一般认为其毒副作用较链霉素,卡那霉素少。近年来随着临床广泛应用,剂量越来越大,适应范围越来越广,因此毒副作用亦日趋增多,甚至有因过敏性休克与急性肾功能衰竭而死亡者。本文就其毒副作用作一综述,旨在提高对庆大霉素合理用药重要性的认识,并指出防 Gentamicin is a broad-spectrum antibiotics, bactericidal power, and generally considered toxic side effects than streptomycin, kanamycin less. In recent years, with the wide application of clinical, more and more dose, the scope of adaptation is more and more wide, so the toxic side effects are also increasing, and even as a result of anaphylactic shock and acute renal failure and death. In this paper, a review of its toxic side effects, aimed at raising the awareness of the importance of rational use of gentamicin, and pointed out that anti