论文部分内容阅读
目的观察并分析西咪替丁与奥美拉唑两种不同药物在治疗应激性胃溃疡中的临床治疗效果。方法 64例应激性胃溃疡患者,随机分成对照组和观察组,各32例,对照组用西咪替丁静脉滴注治疗,观察组采用奥美拉唑静脉滴注治疗,分别观察两组的临床治疗效果,检查并记录止血时间及治疗后的血清胃泌素水平。结果治疗后,观察组的总有效率为90.63%,对照组为68.75%,两组比较差异具有统计学意义(P<0.05)。在胃液pH、血清胃泌素水平以及止血时间上,观察组优于对照组,差异具有统计学意义(P<0.05)。结论在应激性胃溃疡的临床治疗中,奥美拉唑比西咪替丁的疗效更为显著,其可以更有效地降低血清胃泌素水平、缩短止血时间、调节胃内的环境,利于患者溃疡创面的愈合,值得在临床上广泛地推广。
Objective To observe and analyze the clinical effects of two different drugs, cimetidine and omeprazole, in the treatment of stress ulcer. Methods Sixty-four patients with stress ulcer were randomly divided into control group and observation group, with 32 cases in each group. The control group was treated with cimetidine intravenously. The observation group was treated with omeprazole intravenous infusion. Two groups Of the clinical treatment effect, check and record the bleeding time and serum gastrin levels after treatment. Results After treatment, the total effective rate was 90.63% in the observation group and 68.75% in the control group, with significant difference between the two groups (P <0.05). The gastric juice pH, serum gastrin levels and bleeding time, the observation group was better than the control group, the difference was statistically significant (P <0.05). Conclusion Omeprazole is more effective than cimetidine in the clinical treatment of gastric ulcer, which can reduce the level of serum gastrin, shorten the time of hemostasis, regulate the environment in the stomach, Patient ulcer wound healing, it is worth widely in clinical promotion.