“辨证论治”为中医临床独特的理论体系。复方和中药的使用主要是针对相应的“证”,辨证好疗效才好,证变了,药效即有所改变。长期以来,中药实验研究主要沿用西医常用的病理模型,因而受一定“外因论”、“局部定位论”的束缚,观察方法和指标,停留在“病”的概念上,常致造成临床疗效与实验结果间的差距,为全面阐明中药治疗原理带来一定困难。例如,石膏解热作用,至今尚未在实验室证实,有报告对金黄色葡萄球菌、伤寒杆菌、福氏痢疾杆菌等九种病菌均无抑制作用。对伤寒、副伤寒甲、乙菌苗引起的动物发热也无退热作用。张氏等实验发现石膏退热与安替比林相同,效果不持 “Differentiation and Treatment” is a unique theoretical system for TCM clinical practice. The use of compound and traditional Chinese medicines is mainly aimed at the corresponding “certificates”. It is necessary to identify the good curative effects, change the syndrome, and change the efficacy. For a long time, experimental studies of traditional Chinese medicines have mainly used the pathological models commonly used in Western medicine, and thus are bound by certain “external causes” and “local positioning theory”. Observing methods and indicators have stayed in the concept of “disease” and often cause clinical curative effect. The gap between the results of the experiment has brought about certain difficulties in fully elucidating the principle of Chinese medicine treatment. For example, the antipyretic effect of gypsum has not yet been confirmed in the laboratory, and there have been reports of no inhibition on nine kinds of bacteria such as Staphylococcus aureus, Salmonella typhi, and Shigella flexneri. There is no fever effect on animal fever caused by typhoid, paratyphoid A, and B bacterin. Zhang et al found that the antipyretic effect of gypsum is the same as that of antipyrine.