本文报道尼卡迪平对18例冠心病陈旧性心肌梗塞患者心功能效应的观察结果。系用随机、双盲、安慰剂对照设计方法以心脏微分阻抗图各项有关心功能指标在用药前后的改变为依据。尼卡迪平及安慰剂均为20mg,日服3次各连服2周,交叉用药,二药间洗脱期为1周。发现尼卡迪平可降低收缩及舒张血压,降低外周血管阻力,提高血管顺应性、心搏量及心指数。 This article reports the observation of the cardioreflective effects of nicardipine in 18 patients with coronary heart disease and old myocardial infarction. Department of Randomized, Double-blind, placebo-controlled design method of cardiac differential impedance diagram of the various cardiac function indicators before and after treatment based on changes. Nicardipine and placebo were 20mg, served three times a day for 2 consecutive weeks, cross-drug, two drug between the elution period of 1 week. Found that nicardipine can reduce systolic and diastolic blood pressure, reduce peripheral vascular resistance, improve vascular compliance, stroke and cardiac index.