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本文作者对2例疱疹样皮炎(DH)患儿作了如下研究:1.对患儿用大量的谷胶攻击,能否使血清IgA-EmA 由阴性转为阳性?2.IgA-EmA的滴度是否与肠组织病理改变相平行?3.IgA-EmA 的变化是否与皮损临床状况的改变相平行?例1.男,11岁,患DH 2年。2年内在正常饮食情况下隔日用DDS 12.5～25mg,控制了皮损。30周内反复测血清IgA-EmA 持续阴性,空肠活检绒毛无明显变平。食用2 g/kg/d(正常量的4倍)谷胶攻击后反复作血清试验,IgA-EmA 滴度在第8周为2.5,第12周为5,同时皮损复发。于
The authors of the present study examined 2 children with dermatitis herpetiformis (DH) as follows: 1. Whether IgA-EmA is negative to serum IgA-EmA can be switched to positive in children with a large amount of gluten challenge 2. Drops of IgA-EmA Is the degree of parallels with the pathological changes of intestinal tissue? 3.Is the change of IgA-EmA paralleled with the change of the clinical status of lesions? 1. Male, 11 years old with DH for 2 years. 2 years in the case of normal diet DDS 12.5 ~ 25mg every other day, control of the skin lesions. Repeated serum IgA-EmA in 30 weeks continued negative, jejunum biopsy villus did not significantly flatten. Serum tests were repeated after challenge with 2 g / kg / d of glutathione (4 times the normal amount). IgA-EmA titers were 2.5 at week 8, 5 at week 12, and skin lesions relapsed. in