肺心病的血液流变学观察太原市人民医院（０３０００１）王衣慈，魏文京山西医学院第二附属医院高燕，郭存久笔者对我院近３年来收治的肺心病１００例进行了血液流变学观察。报告如下。材料和方法病例选自我院１９９０年到１９９３年３月住院的肺心病人１００例（诊断均符合全国第二次肺心病专业会议修订的慢性肺原性心脏病的诊断标准），男７８例，女２２例，年龄３９～８２岁，平均６４岁，对照组选自健康人体检者８５例，男５６例，女２９例，年龄３５～７６岁，平均６２岁。入院后经过全面检查符合肺心病诊断，进行血液流变学检查采用仪器为上海医科大学产品。晨间空腹采血，血液标本用肝素抗凝，由专人操作。其结果见附表。讨论肺心病由于感染缺氧和二氧化碳潴留，可导致红细胞压积增高，全血及血浆比粘度增高，甚至肺部微血栓形成。全血比粘度低剪切率增高反映红细胞的聚集能力增强。高剪切率增高反映红细胞变形能力降低。文献记载：当氧分压小于５．３３ｋＰａ或二氧化碳分压大于９。３ｋＰａ时红细胞显著变硬，变形性下降，使血粘度增高。肺心病人红细胞聚集力增高，红细胞变形能力低下，促使产生微循环障碍，这在血液流变学上有重要意义。红细胞通过其直径小于本身管径的细血管必须依赖其良好 Pulmonary Heart Disease Hemorheology Observation Taiyuan People’s Hospital (030001) Wang Yi Ci, Wei Wenjing Second Affiliated Hospital of Shanxi Medical College Gao Yan, Guo Cunjiu The author of our hospital nearly three years of pulmonary heart disease treated 100 cases of hemorheology Learn to observe. The report is as follows. Materials and Methods The patients were selected from 100 patients with pulmonary heart disease who were hospitalized from 1990 to March 1993 in our hospital (the diagnostic criteria are in line with the diagnostic criteria of the second national pulmonary heart disease professional conference revised chronic pulmonary heart disease), 78 males, Female 22 cases, aged 39 to 82 years old, average 64 years old, the control group was selected from 85 healthy subjects, 56 males and 29 females, aged 35 to 76 years, mean 62 years. After admission, after a comprehensive examination in line with pulmonary heart disease diagnosis, hemorheology examination using instruments for the Shanghai Medical University products. Morning fasting blood, blood samples with heparin anticoagulation, by hand operation. The results see the schedule. Discussion Pulmonary heart disease due to infection with hypoxia and carbon dioxide retention, can lead to increased hematocrit, whole blood and plasma viscosity, and even pulmonary microthrombus formation. Low whole blood viscosity than shear rate increased reflection of red blood cell aggregation ability. High shear rate increased red blood cell deformability. Literature records: when the oxygen partial pressure is less than 5.33kPa or carbon dioxide partial pressure greater than 9.3kPa significantly hardened red blood cells, deformability decreased, so that blood viscosity increased. Pulmonary heart disease, increased erythrocyte aggregation, red cell deformability, prompting the production of microcirculation, which is of great significance in the blood rheology. The red blood cells must rely on their fine blood vessels through their smaller diameter than their own