酚磺乙胺合成工艺改进靳广毅，曾荣华（山东省医药工业研究所，济南２５０１００）酚磺乙胺作为促凝药，临床上广泛用于手术后防止出血。关于该化合物的合成，目前国内生产工艺均以对苯二醌为原料与二乙肤和二氧化硫生成的复盐反应。该法生产成本较高。我们参考文献［１］... Phenolsulfonamide Synthesis Jin Guangyi, Zeng Ronghua (Institute of Pharmaceutical Industry, Shandong Province, Jinan 250100, China) As the coagulant, phenylenesulfonamide is widely used clinically to prevent bleeding after surgery. With regard to the synthesis of this compound, at present, the domestic production processes all use diphenoquinone as a raw material to react with double salt and sulfur dioxide produced by the double salt reaction. The method of production costs higher. We reference [1] ...