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目的探讨子宫内膜和卵巢原发性双癌的临床病理特点及预后。方法回顾性分析自1995年1月至2006年9月北京大学第一医院诊治的6例子宫内膜和卵巢原发性双癌病例资料。结果6例患者平均年龄为44.7岁,其中3例发生在绝经前。所有患者均接受手术治疗,术后3例病理报告子宫内膜和卵巢均为内膜样癌。5例患者术后接受化疗。全部患者随访3～112个月,1例术后60个月复发,再次接受化疗后病灶消失,所有患者均存活。结论子宫内膜和卵巢原发性双癌不同于单纯子宫内膜癌和卵巢癌,发病年龄早,以内膜和卵巢同为内膜样癌为主要病理类型,首选手术治疗,根据患者情况辅以化疗,预后良好。
Objective To investigate the clinicopathological features and prognosis of primary bilateral endometrium and ovarian cancer. Methods The data of 6 cases of primary endometrial and ovarian primary double cancers diagnosed and treated from the first hospital of Peking University from January 1995 to September 2006 were retrospectively analyzed. Results The average age of 6 patients was 44.7 years, of which 3 occurred in premenopausal women. All patients underwent surgical treatment. Postoperative 3 cases of endometrial and ovarian endometrial carcinoma were reported. Five patients received chemotherapy after surgery. All patients were followed up for 3 to 112 months. One patient relapsed 60 months after operation. The lesions disappeared after chemotherapy and all patients survived. Conclusion The primary bilateral endometrium and ovarian cancer is different from the simple endometrial cancer and ovarian cancer, the age of onset is early, endometrium and ovary with endometrioid carcinoma as the main pathological type, the preferred surgical treatment, according to the patient’s condition supplemented by Chemotherapy, the prognosis is good.