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肝脏是机体重要的代谢器官。胰岛β细胞分泌的胰岛素和α细胞分泌的胰高血糖素,先被肝脏摄取,然后发挥生理效应。所以肝脏对维持血糖的稳定性起着极其重要的作用。慢性肝病特别是肝硬变经常影响糖的代谢和血清胰岛素水平。我们收集33例不同病因的肝硬变,进行口服葡萄糖耐量(OGTT)和胰岛素释放试验(IRT)的研究,以观察肝硬变时肝源性糖尿病患者血浆葡萄糖和胰岛素的变化。材料和方法一、病例选择:收集各种原因引起的肝硬变共33例:其中肝炎后者24例;血吸虫病性者8例;胆汁性者1例。男性27例,女性
The liver is an important metabolic organ of the body. Insulin secreted by pancreatic β cells and glucagon secreted by α cells are first taken up by the liver and then exerted a physiological effect. Therefore, the liver plays an extremely important role in maintaining the stability of blood glucose. Chronic liver disease, especially cirrhosis, often affects the metabolism of sugar and serum insulin levels. We collected 33 patients with cirrhosis of various etiologies and studied oral glucose tolerance (OGTT) and insulin release test (IRT) to observe changes of plasma glucose and insulin in cirrhotic patients with liver-derived diabetes. Materials and methods First, the choice of case: collect a variety of causes of cirrhosis in 33 cases: the latter 24 cases of hepatitis; Schistosomiasis in 8 cases; bile in 1 case. 27 males, females