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为探讨侵犯颅底部骨巨细胞瘤的治疗效果，对近１０年收治的５例该部位的病例作回顾性分析。患者年龄２２～４９岁，平均年龄３６．２岁。４例男性，肿瘤侵犯颅中凹；１例女性，肿瘤破坏枕颈和枕底区。全部病例均采用颅内、外联合途径切除肿瘤，并辅以术后放射治疗。结果表明，侵犯颅底的骨巨细胞瘤可以通过颅内、外联合途径成功地切除，并发症少，无手术死亡率。表明，ＣＴ扫描对于这一部位肿瘤的诊断和手术计划有重要参考意义；术后放疗应作为重要的辅助治疗。
To investigate the treatment of giant cell tumor of the skull at the base of the skull, we retrospectively analyzed the cases of the 5 cases treated in the past 10 years. Patients aged 22 to 49 years, mean age 36.2 years old. 4 cases of male, tumor invasion of cranial cavity concave; 1 case of women, tumor destruction of the occipital and occipital area. All cases were treated by intracranial and external tumor resection combined with postoperative radiotherapy. The results showed that the giant cell tumor of the skull base involving the skull base can be successfully excised by intracranial and external combined approaches with less complications and no operative mortality. Show that CT scan for the diagnosis of this part of the tumor and surgical planning has important reference; postoperative radiotherapy should be an important adjuvant therapy.