病人女 40岁因咳嗽、午后发热半年余,尿及皮肤发黄1天,于1990年11月5日入院。病人于1990年4月诊为肺结核,曾服R、H、E、Z半年余,因无明显症状自行停药半月。入院前3天出现周身不适、寒战、发热,伴恶心、呕吐。11月4日晨服H0.6,R0.45后症状加重,持续性头疼,尿呈酱油色,量少,伴腰痛 Female patient 40 years old due to cough, afternoon fever more than six months, urine and skin yellow 1 day, admitted to hospital on November 5, 1990. The patient was diagnosed as pulmonary tuberculosis in April 1990 and had served for more than half a year for R, H, E and Z. She stopped her medicine for half a month without obvious symptoms. 3 days before admission there was general discomfort, chills, fever, with nausea and vomiting. November 4 morning wear H0.6, R0.45 symptoms worse, persistent headache, urine was soy sauce, less, with low back pain