包虫病(Hydatid disease),是一种严重危害人体健康和影响畜牧业发展的人畜共患寄生虫病。由于传统的病原学方法,诊断该病较困难,故常用影像学和免疫学方法作为辅助诊断手段,尤其免疫学方法以其费用低廉、操作简便、特异性高而成为目前包虫病诊断中的重要手段。但该病免疫学诊断因缺少标准、特异的抗原而影响了实验的敏感性和结果的判定。因此,有必要寻找特异性抗原组分,并进行抗原提纯及免疫原性蛋白组分的分析,以确定标准化的包虫病诊断用抗原,达到与临床诊断标准的统一。 Hydatid disease is a zoonotic parasitic disease that seriously affects human health and affects the development of livestock husbandry. Because of the traditional etiological methods, the diagnosis of the disease more difficult, so commonly used imaging and immunological methods as a diagnostic tool, in particular, immunological methods with its low cost, simple operation, high specificity and become the current diagnosis of hydatid disease Important means. But the immunological diagnosis of the disease due to the lack of standard and specific antigens affect the sensitivity of the experiment and the determination of the results. Therefore, it is necessary to search for specific antigen components, and antigen purification and immunogenic analysis of protein components to determine the standardization of echinococcosis antigen diagnosis, to achieve the unity of clinical diagnostic criteria.