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目的 :研究模拟失重条件下 ,施普瑞螺旋藻对大鼠肠道微生态失调的调整作用。方法 :将基础饲料中加入 5 %的螺旋藻作为处理组饲喂大鼠 ,用选择性培养基分别对肠球菌、肠杆菌、类杆菌、乳杆菌以及双歧杆菌定量测定 ,扫描电镜观察大鼠盲肠上皮细胞的组织变化。结果 :螺旋藻处理组过路菌群中肠杆菌和肠球菌数量变化并不明显 ;原籍菌群中双歧杆菌较对照组显著增多 ,类杆菌和乳杆菌的数量差异没有显著性。模拟失重条件下 SD大鼠盲肠上皮有肿胀细胞出现 ,并且肠道上皮绒毛排列紊乱、稀疏 ,而螺旋藻处理组中只发现有少量的肿胀细胞 ,上皮绒毛致密、排列较整齐。结论 :旋普瑞螺旋藻具有纠正在模拟失重条件下大鼠肠道微生态平衡失调的作用。
OBJECTIVE: To study the regulation effect of Spirulina Spirulina on intestinal microflora imbalance in rats under simulated weightlessness. Methods: The rats were fed with 5% Spirulina platensis as the treatment group, and the Enterococcus, Enterobacter, Bacteroides, Lactobacillus and Bifidobacterium were quantitatively determined by selective medium. The rats were observed by scanning electron microscope Epithelial cecal tissue changes. Results: The number of enterobacteriaceae and enterococci in spore flora of spirulina treatment group was not obvious. The number of bifidobacteria in the indigenous flora was significantly higher than that in the control group, while the number of Bacteroides and Lactobacillus was not significant. In the condition of simulated weightlessness, there were swollen cells in the caecal epithelium of SD rats, and the intestinal epithelial villus arranged disorderly and sparsely. However, only a few swollen cells were found in the spirulina treated group, and the epithelial villi were dense and arranged neatly. Conclusion: Spirulina Spirulina possesses the function of correcting imbalance of intestinal microecology in rats under simulated weightlessness.