目的 :了解成都地区人群中一生中骨折发生的情况及影响因素 ,为防治骨质疏松提供依据。方法 :对四川省成都市≥ 5 0岁的常住人口按整群随机抽样方法抽取 10 930人 (男 5 2 45人 ,女 5 6 85人 )进行既往骨折情况的流行病学调查 ,对影响骨折发生的因素采用非条件单因素和多因素 logistic回归分析方法进行分析。结果 :该人群一生的骨折率为 18.75 % ,女性为 2 1.11% ,男性为 16 .19% ;城市骨折的发生率高于农村 ,分别为 2 7.13%及 12 .2 6 % ,性别及城乡间均有显著性差异(P<0 .0 1)。股骨颈、脊柱和前臂的骨折率分别为 1.42 %、 2 .14%及 4.71%。经 L ogistic回归分析发现 ,骨折与性别、遗传呈正相关 ,与劳动强度、睡眠时间呈负相关 (OR<1)。结论 :人群中发生骨折的危险性女性较男性高 ,城市较农村高 ,劳动强度、睡眠时间、遗传等因素可影响骨折的发生。 OBJECTIVE: To understand the occurrence and influencing factors of life-time fractures in the population of Chengdu and to provide basis for prevention and treatment of osteoporosis. Methods: A total of 10 930 residents (5 455 males and 5 565 females) were enrolled in the randomized sampling of residents ≥50 years old in Chengdu, Sichuan Province to carry out epidemiological investigation of the previous fracture, The occurrence of factors using unconditional univariate and multivariate logistic regression analysis. Results: The lifetime fracture rate was 18.75% in this population, 21.11% in women and 16.19% in men. The incidence of urban fracture in rural areas was higher than that in rural areas (21 7.13% and 12.26%, respectively) There was significant difference (P <0.01). The fracture rates of femoral neck, spine and forearm were 1.42%, 2.14% and 4.71% respectively. L ogistic regression analysis found that the fracture was positively correlated with gender and heredity, negatively correlated with labor intensity and sleep time (OR <1). Conclusion: The risk of fractures in the population of women than men, high urban than rural areas, labor intensity, sleep time, genetic and other factors can affect the occurrence of fractures.