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目的探讨喉罩通气全凭吸入七氟醚在乳腺癌改良根治术中的麻醉效果。方法选取武汉市新洲区妇幼保健院2014年9月—2016年11月收治的乳腺癌患者75例,均行乳腺癌改良根治术治疗。随机分为对照组(n=37)和观察组(n=38)。对照组患者接受传统的静脉注射麻醉诱导,观察组患者则单纯给予高氧流量七氟醚诱导麻醉。记录比较两组患者麻醉诱导时间、喉罩置入时间、清醒时间及喉罩拔除时间及麻醉诱导(T0)、喉罩置入(T1)、手术开始切片(T2)、开始将皮肤缝合(T3)及将喉罩拔除(T4)的平均动脉压(MAP)、心率(HR)及血氧饱和度(SpO_2)。结果两组患者麻醉诱导时间、喉罩置入时间及清醒时间比较,差异无统计学意义(P>0.05);观察组患者喉罩拔除时间短于对照组(P<0.05)。两组患者各时间点HR、SpO_2比较,差异无统计学意义(P>0.05),两组患者T0、T2、T3及T4时间段MAP比较,差异无统计学意义(P>0.05);观察组患者T1时MAP高于对照组(P<0.05)。两组患者T1时MAP低于T0(P<0.05);对照组患者T1的HR低于T0(P<0.05)。结论通过应用喉罩通气全凭吸入七氟醚在行改良根治术的乳腺癌患者中的应用效果良好,可有效缩短患者喉罩拔除时间,充分维持血流动力学稳定。
Objective To investigate the anesthetic effects of laryngeal mask ventilation on total modified radical mastectomy of breast cancer by inhalation of sevoflurane. Methods Seventy-five patients with breast cancer who were treated in Xinzhou District Maternal and Child Health Hospital of Wuhan from September 2014 to November 2016 were treated with modified radical mastectomy of breast cancer. Randomly divided into control group (n = 37) and observation group (n = 38). Patients in the control group received conventional intravenous anesthesia induction and patients in the observation group received induction of sevoflurane alone with high oxygen flow. The anesthesia induction time, laryngeal mask placement time, awake time, laryngeal mask removal time and anesthesia induction (T0), laryngeal mask placement (T1) and operation start slice (T2) were recorded and compared. ), Mean arterial pressure (MAP), heart rate (HR) and oxygen saturation (SpO_2) of the laryngeal mask removed (T4). Results There was no significant difference in anesthesia induction time, laryngeal mask placement time and awake time between the two groups (P> 0.05). The laryngeal mask removal time in the observation group was shorter than that in the control group (P <0.05). There were no significant differences in HR and SpO_2 between the two groups at all time points (P> 0.05). There was no significant difference in MAP between the two groups at T0, T2, T3 and T4 (P> 0.05) MAP was higher in patients with T1 than in controls (P <0.05). The MAP of T1 was lower than T0 in both groups (P <0.05). The HR of T1 in control group was lower than that of T0 (P <0.05). Conclusion The application of laryngeal mask ventilation in patients with modified radical mastectomy due to inhalation of sevoflurane is effective and can effectively shorten the laryngeal mask removal time and maintain hemodynamic stability.