本文报告IgA肾病肉眼血尿对肾功能影响的前瞻性研究结果。方法:对三年内肾活检证实为IgA肾病的21例患者29次肉眼血尿进行初次和随访研究。凡15岁以上,血清肌酐(Scr)增加最少0.5mg/dl或在追踪观察期有类似减少、便被看作肉眼血尿时存在肾功能紊乱,15岁以下,只要Scr变化大于0.3mg/d1则考虑为肾功能改变。按是否合并肾功能减退分为两组。结果:第一组(9例,11次发作)肉眼轿尿发作期间,Scr最高值范围为1.2～6.7mg/dl,肉眼血尿持续时间愈长则肾功能损害愈严重。自血尿发作开始至 This article reports the results of a prospective study of IgA nephropathy with gross hematuria on renal function. Methods: A total of 29 primary gross hematuria in 21 patients with renal biopsy confirmed as IgA nephropathy within three years were studied retrospectively. Anyone over the age of 15 with a minimum serum creatinine (Scr) increase of at least 0.5 mg / dl or a similar decrease at follow-up was considered as having gross dysfunction of the kidney with gross hematuria, under 15 years of age, provided the change in Scr was greater than 0.3 mg / d1 Considered as a change in renal function. According to whether the merger of renal dysfunction is divided into two groups. Results: The first group (9 cases, 11 episodes) of carnitine onset, the highest value of Scr in the range of 1.2 ~ 6.7mg / dl, the longer the gross hematuria, the more serious renal damage. Since the onset of hematuria to