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多发性硬化(MS)是一种以中枢神经白质脱髓鞘为主要病理特点的自身免疫性疾病。既往观点认为与1型辅助T(Th1)细胞、Th17细胞及Th2细胞和调节性T细胞之间的失衡相关,目前发现Th9细胞、Th22及滤泡性辅助性T(Tfh)细胞也与MS发病相关。
Multiple sclerosis (MS) is an autoimmune disease characterized by demyelination of the central white matter. Previously, it is thought that the imbalance between Th1 cells, Th17 cells, Th2 cells and regulatory T cells is related to Th1 cells, Th22 cells and follicular helper T cells. Related.