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脑型疟(cerebral malaria,CM)是引起疟疾患者死亡的主要原因,对其发生分子机制的研究是制定防治策略的前提。早期对脑型疟的研究衍生出两种理论:机械阻塞理论和免疫病理理论,两者一直存在广泛争议。本文就脑型疟机制研究的发展及最新进展作简要的综述。
Cerebral malaria (CM) is the main cause of death in malaria patients. The study of its molecular mechanism is the prerequisite for the development of prevention and treatment strategies. Early studies of cerebral malaria derived two theories: mechanical blockage theory and immunopathology theory, there has been widespread controversy between the two. This article gives a brief overview of the development of research on the mechanism of cerebral malaria and the latest progress.