论文部分内容阅读
博来霉素目前已分离出纯的组份11种,并已阐明其结构。在发现博来霉素以后,为了寻找抗肿瘤作用强且副作用小的抗癌药,又做了许多基础研究。到现在研制的博来霉素衍生物已达300种以上。其中有一个是 Pepleomycin(末端氨基是3—[1—(S)—苯乙氨基]—丙氨基)。
Bleomycin has so far isolated 11 pure components and has elucidated its structure. In the discovery of bleomycin, in order to find anti-tumor effect and side effects of small anti-cancer drugs, done a lot of basic research. Now up to 300 kinds of bleomycin derivatives have been developed. One of them is Pepleomycin (the terminal amino group is 3- [1- (S) -phenylethylamino] -propylamino).