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环孢素 (ｃｙｃｌｏｓｐｏｒｉｎｅＡ ,ＣｓＡ)是从土壤霉菌中分离出来的含有 11个氨基酸的环形多肽 ,能阻止细胞毒Ｔ淋巴细胞前体细胞的激活 ,并选择性地抑制辅助性Ｔ淋巴细胞分泌白介素 2和其他淋巴因子 ,因而是一种强效免疫抑制剂[1] 。ＣｓＡ的临床应用使器官移植取得了划
Cyclosporine A (CsA) is a cyclic polypeptide with 11 amino acids isolated from soil mold, which can prevent the activation of cytotoxic T lymphocyte precursor cells and selectively inhibit the secretion of interleukin 2 by helper T lymphocytes And other lymphokines, it is a potent immunosuppressive agent [1]. The clinical application of CsA made the plan of organ transplantation