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目的探讨新生儿先天性十二指肠隔膜症的临床表现、诊断方法及治疗。方法回顾性分析2010年9月至2013年9月我院新生儿科收治的十二指肠隔膜症新生儿病例资料,总结临床特点及诊治情况。结果 13例先天性十二指肠隔膜症的新生儿住院期间均表现为喂养困难、呕吐明显,多伴有胆汁性呕吐,其中8例通过上消化道造影诊断,3例为先天性肠旋转不良手术中发现诊断,2例通过纤维胃镜检查确诊,平均确诊日龄为14.5天,最迟诊断日龄为41天。11例通过手术治疗治愈出院,1例自动出院,1例合并新生儿坏死性小肠结肠炎放弃抢救死亡。结论先天性十二指肠隔膜症可能是新生儿喂养困难的重要原因之一,上消化道造影及胃镜在诊断中有重要意义,手术是治疗十二指肠隔膜症的有效方法。
Objective To investigate the clinical manifestations, diagnosis and treatment of neonatal congenital duodenal septal disease. Methods A retrospective analysis of neonatal cases of duodenal septal disease treated in our hospital from September 2010 to September 2013 was conducted to summarize the clinical features and diagnosis and treatment. Results Thirteen cases of congenital duodenal septal disease during hospitalization were characterized by difficulty in feeding, vomiting, and more associated with bile vomiting. Among them, 8 cases were diagnosed by upper gastrointestinal angiography and 3 cases were congenital intestinal malrotation Diagnosis was found in the operation, 2 cases were diagnosed by gastroscopy, the average diagnosis day was 14.5 days, the latest diagnosis day was 41 days. Eleven patients were discharged by surgery, one patient was discharged automatically, and one patient died of necrotizing enterocolitis with newborn. Conclusions Congenital duodenal septum disease may be one of the important causes of neonatal feeding difficulties. Upper gastrointestinal angiography and endoscopy are important in the diagnosis. Surgery is an effective method for the treatment of duodenal septal disease.