苄苯哌咪唑[astemizole(hismanal;janssen)]是H_1组胺受体拮抗剂,作用维持时间长,可每日给药1次。已证实苄苯哌咪唑对于季节性或持久性的过敏性鼻炎有效。一系列研究提示苄苯哌咪唑的疗效至少与其它H_1组胺受体拮抗剂相同。不具中枢神经系统的抑制作用在志愿者试验中,苄苯哌咪唑单剂量40mg能明显抑制皮下注射组胺所引起的水肿与发红反应。志 Astemizole (hismanal; janssen)] is a H 1 histamine receptor antagonist, the role of maintaining a long time, can be administered once daily. Benzypeline has been shown to be effective for seasonal or persistent allergic rhinitis. A series of studies suggest that the efficacy of benazepam is at least as good as that of other H 1 histamine receptor antagonists. Inhibition of the Central Nervous System In a volunteer trial, a single 40 mg dose of benzylbenzimid significantly inhibited edema and redness induced by subcutaneous injection of histamine. Chi