论文部分内容阅读
目的探讨亚临床甲状腺功能低下(SCH)与不良妊娠结局的相关性以及药物干预对妊娠结局的影响。方法 50例SCH孕妇及52例经左旋甲状腺素(L-T4)治疗SCH孕妇,100例同期甲功正常的妊娠妇女作对照组,进行妊娠结局分析比较。结果 (1)未用药SCH孕妇分别与用L-T4治疗及甲功正常孕妇比较,其在早产、产后出血、足月小于胎龄儿发生率均显著增高(P<0.05)。(2)用药SCH孕妇与甲功正常妊娠妇女在早产、产后出血、足月体重小于胎龄儿发生率差异无统计学意义(P>0.05)。结论 SCH可增加不良妊娠结局发生,早期筛查可改善不良妊娠结局发生。
Objective To investigate the correlation between subclinical hypothyroidism (SCH) and adverse pregnancy outcomes and the effect of drug intervention on pregnancy outcome. Methods A total of 50 pregnant women with SCH and 52 pregnant women with SCH were treated with L-T4, and 100 pregnant women with normal thymectomy during the same period were selected as control group. Pregnancy outcomes were analyzed and compared. Results (1) Compared with L-T4 treatment and normal pregnant women with normal thyroid function, pregnant women without SCH were significantly more likely to have preterm birth and postpartum hemorrhage than those with full gestational age (P <0.05). (2) medication SCH pregnant women and normal women with normal pregnancy in preterm birth, postpartum hemorrhage, full-term body weight less than the incidence of gestational age was no significant difference (P> 0.05). Conclusion SCH can increase the incidence of adverse pregnancy outcomes, early screening can improve the outcome of adverse pregnancy outcomes.