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目的探析不同用药方案对初治活动性肺结核疗效的影响。方法选择广东新会结核病防治所2013年3月至2014年8月收治77例初治活动性肺结核患者作为研究对象,随机分为A组(n=39)与B组(n=38)。A组采取每日服药,B组采取隔日服药,比较两组治疗有效率与不良反应发生率。结果 A组治疗总有效率为94.9%,高于B组的86.8%,但差异未见统计学意义(P>0.05)。A组不良反应发生率为10.3%,低于B组的28.9%,差异有统计学意义(P<0.05)。结论每日疗法与隔日疗法各有优势,疗效肯定,对于年老体弱患者建议采取每日服药疗法以减少不良反应。
Objective To explore the effect of different medication regimens on the curative effect of newly diagnosed active pulmonary tuberculosis. Methods A total of 77 patients with newly diagnosed active pulmonary tuberculosis from March 2013 to August 2014 were enrolled in this study. Patients were randomly divided into group A (n = 39) and group B (n = 38). A group take daily medication, B group take every other day medication, compare the two groups of treatment efficiency and adverse reaction rate. Results The total effective rate of treatment in group A was 94.9%, which was higher than that in group B 86.8%, but the difference was not statistically significant (P> 0.05). The incidence of adverse reactions in group A was 10.3%, which was lower than that in group B (28.9%), the difference was statistically significant (P <0.05). Conclusion Daily therapy and every other day treatment have their own advantages, efficacy is positive, for the elderly and frail patients suggest daily medication to reduce adverse reactions.