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目的研究等渗造影剂碘克沙醇对冠状动脉造影具造影剂肾病高危因素患者肾功能的影响。方法选择具有冠状动脉造影适应症患者30例,对患者造影术前及术后第1、2、3天肾功能生化血肌酐(Cr)、尿素氮(Bun)、二氧化碳结合力(CO2CP)进行比较。结果30例患者冠状动脉造影术前及术后第1、2、3天Cr、Bun、CO2CP虽有波动,但无明显改变(P>0.05)。结论等渗造影剂碘克沙醇对冠状动脉造影具造影剂肾病高危因素患者肾功能无明显影响。
Objective To study the effect of isotonic contrast agent iodixanol on renal function in patients with coronary artery angiography who had risk of contrast nephropathy. Methods Thirty patients with indications of coronary angiography were selected and their renal biochemical serum creatinine (Cr), urea nitrogen (BUN) and carbon dioxide binding capacity (CO2CP) were compared before and after angiography . Results There were no significant changes in Cr, Bun and CO2CP before coronary angiography and at the first, second and third days after operation in 30 patients (P> 0.05). Conclusions Isotonic contrast agent iodixanol has no significant effect on renal function in patients with coronary angiography who are at risk of contrast nephropathy.