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本实验观察并比较了参附注射液及其主要成分(人参总皂甙、附子总生物碱)对大鼠心肌细胞膜ATP酶活性的影响,结果表明参附注射液及其主要成分人参总皂甙和附子总碱对心肌细胞膜ATP酶均有抑制作用,与二种主要成分比较,参附注射液的抑制作用明显增强(P<0.025;P<0.0025);提示参附注射液可能具有不同程度的正性肌力作用。
This experiment observed and compared the effects of Shenfu Injection and its main components (total ginsenosides and total alkaloids of Radix Aconiti Lateralis) on ATPase activity of myocardial cell membrane in rats. The results showed that Shenfu Injection and its main components ginsenosides and aconite Total alkaloids had inhibitory effects on myocardial cell membrane ATPase. Compared with the two main components, the inhibitory effect of Shenfu injection was significantly increased (P<0.025; P<0.0025); suggesting that Shenfu injection may have different degrees of positive Muscle effect.