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目的了解户外空气质量与出生缺陷发生的关系,为病因预防提供参考。方法利用空气质量和出生缺陷的监测资料,采用生态趋势研究的方法,统计方法采用卡方检验。结果在控制了部分混杂因素后,2003年至2007年广州市出生缺陷的发生率总体呈上升的趋势,与2002~2006年广州市户外空气质量的变化趋势基本一致,卡方检验无显著性差异。结论户外空气质量与出生缺陷发生率的变化存在一定的相关性,建议医疗保健机构与环境控制部门建立信息交流和协作,共同致力于环境保护,减少出生缺陷等不良妊娠结局的发生。
Objective To understand the relationship between outdoor air quality and birth defects and provide references for the prevention of etiology. Methods Using the monitoring data of air quality and birth defects, the methods of ecological trend research were used, and the statistical methods were chi-square test. Results After controlling for some confounding factors, the incidence of birth defects in Guangzhou showed an overall upward trend from 2003 to 2007, which was basically in line with the change trend of outdoor air quality in Guangzhou from 2002 to 2006. There was no significant difference in chi-square test . Conclusion There is a certain correlation between outdoor air quality and the incidence of birth defects. It is suggested that health care institutions and environmental control departments should establish information exchange and cooperation to jointly commit to environmental protection and reduce the occurrence of adverse pregnancy outcomes such as birth defects.