论文部分内容阅读
目的：观察异丙酚、氯胺酮复合液在小儿椎管内阻滞麻醉的辅助效果。方法：择期患儿腹部、下肢 及会阴部手术９０例，随机将患者分为Ｋ组：氯胺酮、γ－ＯＨ组；Ｐ组：异丙酚组；ＰＫ组：异丙酚、氯胺酮复合液 组。结果：氯胺酮用量Ｋ组比ＰＫ组显著升高（Ｐ＜０．０１），异丙酚用量Ｐ组显著升高（Ｐ＜０．０１）。用药后血压 变化：Ｋ组和ＰＫ组显著升高（Ｐ＜０．０５），Ｐ组显著下降（Ｐ＜０．０５），但三组均在正常范围，３０ｍｉｎ趋稳定。术中 镇静计分Ｐ组偏低３．８＋０．０５分，其余两组均达４分以上。体动次数Ｋ组、Ｐ组较ＰＫ组显著增加（Ｐ＜０．０１）。 术后苏醒时间ＰＫ组与Ｐ组接近，同Ｋ组比较显著缩短（Ｐ＜０．０１），术后呕吐次数ＰＫ组与Ｐ组较Ｋ组显著减 少（Ｐ＜０．０１）。结论：异丙酚、氯胺酮复合液用于小儿椎管内阻滞麻醉辅助效果确切，术中呼吸循环稳定，不 影响术后苏醒，无明显恶心、呕吐。
Objective: To observe the auxiliary effect of propofol and ketamine compound solution in pediatric spinal block anesthesia. Methods: Totally 90 children undergoing abdominal surgery, lower extremity and perineal surgery were randomly divided into K group: ketamine and γ-OH group; P group: propofol group; PK group: propofol and ketamine complex solution group. Results: Ketamine dosage in K group was significantly higher than that in PK group (P <0.01), and propofol dosage was significantly increased in P group (P <0.01). Blood pressure changes after treatment: K group and PK group were significantly increased (P <0.05), P group decreased significantly (P <0.05), but the three groups were in the normal range, 30min trend stable. Intraoperative sedation score P group low 3.8 + 0.05 points, the remaining two groups were up to 4 points or more. The frequency of body movement in K group and P group was significantly higher than PK group (P <0.01). The recovery time of PK group was close to that of P group and significantly shorter than that of K group (P <0.01). The number of postoperative vomiting was significantly decreased in PK group and P group as compared with K group (P <0.01). CONCLUSION: Propofol and ketamine compound solution are effective in anesthesia in pediatric spinal canal block. The intraoperative respiration cycle is stable and does not affect the postoperative recovery. There is no obvious nausea and vomiting.