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目的探讨膳食摄入水平及生化指标与非酒精性脂肪性肝病的相关关系。方法对2010年至2012年在济南市某医院健康体检的1284名女性进行膳食调查、身体测量及血清生化指标检测。结果济南市女性各类食物的摄入量与《中国居民平衡膳食宝塔》推荐量相比,膳食中油类的摄入量高于推荐摄入量;约一半人群谷类、蔬菜类、蛋类、畜禽肉类、水果类、大豆类及坚果的摄入量能满足推荐量;70%以上人群鱼虾类、奶类及其制品摄入量低于推荐量。脂肪肝组平均每日摄入的谷类、畜禽肉类、蛋类、豆类及坚果类和食用油均显著高于非脂肪肝组;脂肪肝组水果的摄入量显著低于非脂肪肝组(175.8 vs.205.4 g/d,P<0.05)。多因素Logistic回归分析表明,年龄在41~50和51~65岁者、摄入超过推荐量的鱼虾类、食用油,超重、肥胖、腰臀比、总胆固醇、甘油三酯和血尿酸水平可使脂肪肝患病的危险性增加,优势比分别为2.716、3.066、4.164、2.256、2.524、4.698、2.658、1.674、2.280、3.286。结论年龄、膳食摄入水平、肥胖与非酒精性脂肪性肝病的发生有密切关联;摄入超过推荐量的鱼虾类和食用油是非酒精性脂肪性肝病患病的危险因素。
Objective To investigate the relationship between dietary intake and biochemical markers and non-alcoholic fatty liver disease. Methods A total of 1,284 women from a hospital in Jinan City from 2010 to 2012 were surveyed for dietary measurements, body measurements and serum biochemical indexes. Results The intake of various types of food for women in Jinan was higher than the recommended intake of “Chinese residents balanced diet pagoda”. The intake of oil in the diet was higher than the recommended intake. About half of the population consumed cereals, vegetables, eggs, livestock Poultry meat, fruits, soybeans and nuts intake to meet the recommended amount; 70% of the population of fish, shrimp, dairy products and their intake of less than the recommended amount. Fatty liver group average daily intake of cereals, livestock and poultry meat, eggs, beans and nuts and cooking oil were significantly higher than non-fatty liver group; fatty liver group intake of fruit was significantly lower than non-fatty liver Group (175.8 vs. 205.4 g / d, P <0.05). Multivariate logistic regression analysis showed that the intake of fish and shrimp, edible oil, overweight, obesity, waist-hip ratio, total cholesterol, triglyceride and blood uric acid levels in the 41 to 50 and 51 to 65 years old groups Can increase the risk of fatty liver disease, odds ratio were 2.716,3.066,4.164,2.256,2.524,4.698,2.658,1.674,2.280,3.286. Conclusion Age, dietary intake and obesity are closely related to the occurrence of non-alcoholic fatty liver disease. Fish, shrimp and cooking oil in excess of the recommended intake are risk factors for nonalcoholic fatty liver disease.