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不少作者认为生物膜的脂质过氧化可能是许多化学毒物毒性作用的起点;而二氧化硅粉尘对生物膜的脂质过氧化也具有一定的影响,对此已在吞噬细胞或红细胞的培养过程中得到证实。 本研究是用体外实验方法,观察二氧化硅粉尘对大鼠肺组织脂质过氧化的影响,以探讨脂质过氧化在矽肺发病过程中的作用。
Many authors believe that lipid peroxidation of biofilms may be the starting point of many toxic effects of chemical poisons; and silica dust has a certain impact on the biofilm lipid peroxidation, which has been in the phagocyte or red blood cell culture The process has been confirmed. The purpose of this study is to investigate the effect of silica dust on lipid peroxidation in rat lung tissue in vitro and to explore the role of lipid peroxidation in the pathogenesis of silicosis.